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Let¡¯s face it, organic chemistry can seem difficult to learn. 318276-72-1. Especially from a beginner¡¯s point of view. Like 318276-72-1, Name is 6-Bromocinnoline. In a document type is Article, introducing its new discovery.

New efficient method for the synthesis of chiral 2,2?-bipyridyl ligands

An efficient preparation of chiral 2,2?-bipyridines was developed. Compound 1 was synthesized in 54% yield for three steps starting from 2,6-dibromopyridine. In this synthesis, only catalytic amounts of metals were used in the asymmetric reduction and homo-coupling reaction steps. The total yield and simplicity of experimental procedures were much improved compared with those of the previous report. Other chiral 2,2?-bipyridines were similarly synthesized with high efficiency. Georg Thieme Verlag Stuttgart.

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Reference£º
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics