Top Picks: new discover of 137195-33-6

There is still a lot of research devoted to this compound(SMILES:O=C1CNNC2=C1C=CC=C2.[H]Cl)Safety of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride, and with the development of science, more effects of this compound(137195-33-6) can be discovered.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Pharmazie called Synthesis and action on the central nervous system of some N2-substituted cinnoline derivatives, Author is Stanczak, A.; Kwapiszewski, W.; Szadowska, A.; Pakulska, W., which mentions a compound: 137195-33-6, SMILESS is O=C1CNNC2=C1C=CC=C2.[H]Cl, Molecular C8H9ClN2O, Safety of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride.

Alkylation of 4-hydroxycinnolines using Et bromoacetate resulted in N2-substituted acetic acids. These acids were converted to esters and amides. Some of the obtained acids were reduced with zinc dust to give 4-oxo-1,2,3,4-tetrahydro-2-cinnolineacetic acids. Several of the compounds were tested for their effect on central nervous system.

There is still a lot of research devoted to this compound(SMILES:O=C1CNNC2=C1C=CC=C2.[H]Cl)Safety of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride, and with the development of science, more effects of this compound(137195-33-6) can be discovered.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics