The important role of 21905-86-2

21905-86-2,big data shows that is playing an increasingly important role.

21905-86-2,Cinnoline-4-carboxylic acid,C9H6N2O2,SMILES CODES_O=C(C1=C2C=CC=CC2=NN=C1)O,is widely used in the synthesis of drugs.

EXAMPLE 2 Potassium Cinnoline-4-carboxylate (2) 5.10 g of (1) was added over 30 minutes to a vigorously stirred solution of 2.02 g of potassium carbonate in 25 ml of water, at room temperature. The resulting mixture was stirred for one hour at room temperature, then treated with charcoal, and after filtration the water was evaporated. The residue was azeotropically distilled with toluene and dried at 70 C. under reduced pressure, to give 2, as a light tan powder, m.p.: above 280 C.

21905-86-2,big data shows that is playing an increasingly important role.

Reference£º
Patent; E. I. Du Pont de Nemours and Company; US4699651; (1987); A;,
Cinnoline – Wikipedia
Cinnoline – an overview | ScienceDirect Topics